The role of growth factors in self-renewal and differentiation of human embryonic stem cells – Ing. Lívia Eiselleová, Ph.D.
Ing. Lívia Eiselleová, Ph.D.
Doctoral thesis
The role of growth factors in self-renewal and differentiation of human embryonic stem cells
The role of growth factors in self-renewal and differentiation of human embryonic stem cells
Abstract:
Lidské embryonální kmenové (EK) buňky jsou charakterizovány schopností sebeobnovy a pluripotence. Regulační mechanismy podmiňující tyto vlastnosti závisí na vnitřních a vnějších programech, přičemž ty vnější jsou zabezpečovány okolním mikroprostředím známým jako nika. Většina linií lidských EK buněk je kultivována v přítomnosti tzv. „feedrových“ podpůrných buněk, které umožňují jejich přichycení, poskytují …moreAbstract:
Human embryonic stem cells (hESCs) are characterized through their self-renewal capacity and pluripotency. The underlying regulatory mechanism to maintain these characteristics is based on both extrinsic and intrinsic programs where extrinsic signals are provided by external microenvironment, so-called niche. Most of hESCs lines are co-cultured with feeder cells that improve their attachment and provide …more
Language used: English
Date on which the thesis was submitted / produced: 27. 1. 2012
Identifier:
https://is.muni.cz/th/cix80/
Thesis defence
- Date of defence: 27. 1. 2012
- Supervisor: prof. Ing. Petr Dvořák, CSc.
Citation record
ISO 690-compliant citation record:
EISELLEOVÁ, Lívia. \textit{The role of growth factors in self-renewal and differentiation of human embryonic stem cells}. Online. Doctoral theses, Dissertations. Brno: Masaryk University, Faculty of Medicine. 2012. Available from: https://theses.cz/id/j6y2jp/.
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Institution archiving the thesis and making it accessible: Masarykova univerzita, Lékařská fakultaMasaryk University
Faculty of MedicineDoctoral programme / field:
Medical Biology (4-years) / Medical Biology
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