Human Embryonic Stem Cells: Cell Cycle Regulation and Reaction to DNA damage – Mgr. Tomáš Bárta, Ph.D.
Mgr. Tomáš Bárta, Ph.D.
Doctoral thesis
Human Embryonic Stem Cells: Cell Cycle Regulation and Reaction to DNA damage
Human Embryonic Stem Cells: Cell Cycle Regulation and Reaction to DNA damage
Abstract:
Lidské embryonální kmenové (EK) buňky nacházejí uplatnění v mnoha biomedicínských aplikacích. Avšak než bude možné plně využít jejich potenciál, je zapotřebí zcela pochopit jejich biologii. Schopnost EK buněk udržovat si pluripotentní stav během kultivace in vitro vyžaduje unikátní konfiguraci molekul, které regulují buněčný cyklus. Molekulární mechanismy, které umožňují EK buňkám uchovávat si jejich …moreAbstract:
Human embryonic stem (hES) cells hold great promise in many biomedical applications including cell replacement therapy, drug screening and developmental studies. However, before the full potential of these cells can be applied, we must deeply understand the biology of these cells. Particularly, the cell cycle regulation and genome integrity maintenance is very important for eliminating concerns regarding …more
Language used: English
Date on which the thesis was submitted / produced: 4. 9. 2012
Identifier:
https://is.muni.cz/th/dnt0h/
Thesis defence
- Date of defence: 19. 10. 2012
- Supervisor: doc. MVDr. Aleš Hampl, CSc.
Citation record
ISO 690-compliant citation record:
BÁRTA, Tomáš. \textit{Human Embryonic Stem Cells: Cell Cycle Regulation and Reaction to DNA damage}. Online. Doctoral theses, Dissertations. Brno: Masaryk University, Faculty of Medicine. 2012. Available from: https://theses.cz/id/lw5ak5/.
Full text of thesis
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Published in Theses:- světu
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Institution archiving the thesis and making it accessible: Masarykova univerzita, Lékařská fakultaMasaryk University
Faculty of MedicineDoctoral programme / field:
Medical Biology (4-years) / Medical Biology
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