Mgr. Jan Coufal, Ph.D.

Doctoral thesis

Interakce proteinů p53, IFI16 a 14-3-3 s křížovými strukturami in vitro a in vivo

Interactions of proteins p53, IFI16 and 14-3-3 with cruciform structures in vitro and in vivo
Abstract:
Tato práce se zabývá proteiny p53, IFI16 a 14-3-3, které jsou zahrnuty v nejrůznějších signálních drahách a interagují s DNA. Práce je zaměřena na interakci zmíněných proteinů s DNA a s křížovými strukturami in vitro a in vivo.
Abstract:
This work is focused on p53, IFI16 and 14-3-3 proteins, which are involved in various signalling pathways and are capable of binding DNA. Main focus is on interaction of these proteins with DNA and cruciform structures in vitro and in vivo.
 
 
Language used: Czech
Date on which the thesis was submitted / produced: 4. 3. 2016

Thesis defence

  • Date of defence: 29. 4. 2016
  • Supervisor: doc. Mgr. Václav Brázda, Ph.D.
  • Reader: doc. Mgr. Jan Paleček, Dr. rer. nat., RNDr. Iva Kejnovská, CSc.

Citation record

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Institution archiving the thesis and making it accessible: Masarykova univerzita, Přírodovědecká fakulta